Sheffield United striker Oli McBurnie will miss the rest of their season after suffering a foot fracture.
The Scotland international picked up the problem during the recent 3-0 defeat to Arsenal.
The news comes a day after skipper Billy Sharp revealed he would not play again this campaign.
McBurnie’s teammate has undergone surgery on a thigh problem sustained in training.
The Blades face Nuno Espirito Santo’s Wolves on Saturday April 17.
At the pre-match press conference, boss Paul Heckingbottom said: “Oli is out for the season as well.
“He’s got a stress fracture in his fifth metatarsal so we’ve lost two forwards, which isn’t positive.”
Sharp had his operation on Wednesday and is aiming to return for the 2021/22 pre-season.
Heckingbottom added: “His procedure has gone well. It’s a tendon issue that required surgery for the best chance of recovery, rather than rest which we were hoping for.
“It’s a blow because we were hoping we’d have him back for the last few games of the season. But as far as I’m aware, pre-season is the aim.
“The procedure was yesterday and we’ve just had a little bit of an update. I’ve been there as a player and you just want to know what’s next as there’s a real mental side to an injury like that, especially when it’s worse than first feared.
“His presence will be missed, I want every player fit and someone of Sharpy’s experience and his connection with the club, and being club captain, it’s a big loss for us for a lot of reasons – not just on the pitch.
“We seem to get one player back and lose two at the minute but that’s how it is, and it tends to be the way when things aren’t going to your way.”
Sheffield United have struggled in front of goal during this tough season.
David McGoldrick is their top scorer with just seven goals. After him it’s Sharp with five and wing-back Jayden Bogle with three.
The injuries to Sharp and McBurnie won’t help their cause.
Following the game against Wolves, they host Brighton at Bramall Lane on Saturday April 24.